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Name Way-Zen Lee
Lab TEL (02)77496186
Office TEL (02)77496133
FAX No. (02)29324249
Address. (11677)No. 88, Sec. 4, Ting-Chow Rd, Taipei, Taiwan, 11677, R.O.C.
E-mail wzlee@ntnu.edu.tw
Lab. Website http://www.chem.ntnu.edu.tw/~wzlee/
Classification Full-Time
Title Professor
Research Bioinorganic Chemistry, Organometallics, and Bioinspired Catalysis
Research Specialization  
Student 柯名時 / 蔡方元 / 張智凱 / 楊人翰 / 楊詠剴 / 蔡杰紘 / 林庚鋒 / 廖翊雅 / 林雅慧 / 高均其 / 柳正元 / 陳志銘 / 朱允立 / 林宗翰 / 莊淑雅 / 王維鈴 / 陳許志勇 / 史南卡
Laboratory Bioinorganic Chemistry Research Lab /

Academic Researches

  1. Journal Articles
    1. T. Chatterjee, B. Molnar, W.-Z. Lee,* K. V. Lakshmi,* and M. Ravikanth* “Calixsmaragdyrin: A Versatile Ligand for Coordination Complexes” Inorg. Chem201756, 3763-3772.
    2. J.-H. Fang, J.-H. Jian, H.-C. Chang, T.-S. Kuo, W.-Z. Lee, P.-Y. Wu, and H.-Liang Wu* "Synthesis of Quaternary-Carbon-Containing β2,2-Amino Acids by the RhI-Catalyzed Enantioselective Arylation of α-Substituted β-NitroacrylatesChem. Eur. J. 201723, 1830-1838.
    3. C.-C. Wang, H.-C. Chang, Y.-C. Lai, H. Fang, C.-C. Li, H.-K. Hsu, Z.-Y. Li, T.-S. Lin, T.-S. Kuo, F. Neese, S. Ye,* Y.-W. Chiang,* M.-L. Tsai,* W.-F. Liaw,* and W.-Z. Lee* “A Structurally Characterized Nonheme Cobalt-Hydroperoxo Complex Derived from its Superoxo Intermediate via Hydrogen Atom Abstraction” J. Am. Chem. Soc. 2016138, 14186-14189.
    4. T. Kaur, W.-Z. Lee and M. Ravikanth* “Rhenium(I) Tricarbonyl Complexes of meso-Tetraaryl-21,23-diheteroporphyrins” Inorg. Chem. 201655, 5305-5311.
    5. H. D. Stout, S. T. Kleespies, C.-W. Chiang, W.-Z. Lee, L. Que, Jr., E. Münck,* and E. L. Bominaar* “Spectroscopic and Theoretical Study of Spin-Dependent Electron Transfer in an Iron(III) Superoxo Complex” Inorg. Chem. 201655, 5215-5226.
    6. T. Kaur, W.-Z. Lee and M. Ravikanth* “N-Methylated 25-Oxasmaragdyrins: Synthesis, Structure and Properties” J. Porphyr. Phthalocyanines 201620, 582-589.
    7. T. Chatterjee, W.-Z. Lee and M. Ravikanth* “Stabilization of Hexa-Coordinated P(V) Corroles by Axial Silyloxy Groups” Dalton. Trans201645, 7815-7822.
    8. C.-C. Chou,* C.-C. Yang, H.-C. Chang, W.-Z. Lee* and T.-S. Kuo “Weaving an infinite 3-D supramolecular network via AuI⋯AuIII aurophilicity and C-H⋯Cl hydrogen bonding” New J. Chem201640, 1944-1947.
    9. H.-C. Chang, Y.-C. Hsu, C.-H. Chen, T.-S. Kuo and W.-Z. Lee* “Thioiminium and thiaphospholanium derived from acetonitrile via nickel(II)–(2-mercaptophenyl)phosphine complexations” Dalton Trans201544, 20808-20811.
    10. R. Sharma, W.-Z. Lee, and M. Ravikanth* “Formation of Unusual Dithiaphlorins from Condensation of 2,5-bis(Arylhydroxymethyl)thiophene and Pyrrole” RSC Adv. 20155, 102765-102771.

    11. H. Kalita, W.-Z. Lee, G.-G. Theophall, K.-V. Lakshmi, and M. Ravikanth* “A Stable Seven-Membered Heterocycle, Containing B, C, N, O, and P Atoms, inside a Smaragdyrin Macrocycle” Chem. Eur. J. 2015, 21, 11315-11319.
    12. E. Ganapathi, T Chatterjee, W.-Z. Lee and M. Ravikanth* “Synthesis, Structure, and Properties of Core-modified Pentaphyrins Containing Six mesoCarbons” Asian J. Org. Chem. 20154, 638-645.
    13. H.-C. Chang, F.-C. Lo, W.-C. Liu, T.-H. Lin, W.-F. Liaw, T.-S. Kuo, and W.-Z. Lee* “Ambient Stable Trigonal Bipyramidal Copper(III) Complexes Equipped with an Exchangeable Axial Ligand” Inorg. Chem201554, 5527-5533.
    14. Y. Meesala, V. Kavala, H.-C. Chang, T.-S. Kuo, C.-F. Yao,* and W.-Z. Lee* “Anilido-Benzoxazole Boron Difluoride (ABB) Complexes: Novel bright fluorescent dyes in solution and in the solid state” Dalton Trans201544, 1120-1129.
    15. V. Lakshmi, W.-Z. Lee, and M. Ravikanth* "Synthesis, structure and spectral and electrochemical properties of 3-pyrrolyl BODIPY-metal dipyrrin complexes" Dalton Trans201443, 16006-16014.
    16. E. Ganapathi, W.-Z. Lee,* and M. Ravikanth* "Stable Nonaromatic [20]Dithiaporphyrin ( Macrocycles: Synthesis, Structure, Spectral, Electrochemical and Metal Ion Sensing Studies” J. Org. Chem. 201479, 9603-9612.
    17. Y. Meesala, H.-L. Wu, B. Koteswararao, T.-S. Kuo, and W.-Z. Lee* “Aerobic Oxidative Coupling of 2-Naphthol Derivatives Catalyzed by a Hexanuclear Bis(μ-hydroxo)Copper(II) Catalyst” Organometallics 201433, 4385-4393.
    18. H. Kalita, W.-Z. Lee, and M. Ravikanth* "Phosphorus Complexes of meso-Triaryl-25-oxasmaragdyrinsInorg. Chem. 201453, 9431-9438.
    19. H. Kalita, D. Kalita, W.-Z. Lee, J. Bellare, and M. Ravikanth* “Synthesis of meso-Pyrrole-Substituted 22-Oxacorroles by a "3+2" Approach” Chem. Eur. J. 2014, 20, 10404-10413.
    20. C.-W. Chiang, S. Kleespies, H. Stout, K. Meier, P.-Y. Li, E. Bominaar,* L. Que, Jr.,* E. Münck,* and W.-Z. Lee* “Characterization of a Paramagnetic Mononuclear Nonheme Iron-Superoxo Complex” J. Am. Chem. Soc. 2014136, 10846-10849.
    21. T. Kaur, W.-Z. Lee, and M. Ravikanth* "N-Methyl-21-thiaprophyrinsEur. J. Org. Chem. 2014, 2261-2267.
    22. C.-W. Chiang, Y.-L. Chu, H.-L. Chen, T.-S. Kuo, and W.-Z. Lee* “Synthesis and Characterization of NiIIIN3S2 Complexes as Active Site Models for the Oxidized Form of Nickel Superoxide Dismutase” Chem. Eur. J. 2014, 20, 6283-6286.
    23. E. Ganapathi, W.-Z. Lee* and M. Ravikanth* “Synthesis, Structure, Spectral and Electrochemical Properties of Meso-Tetraaryl 27-Thiasapphyrins” Asian J. Org. Chem. 20143, 290-296.
    24. B. Gopula, C.-W. Chiang, W.-Z. Lee, T.-S. Kuo, P.-Y. Wu, J. P. Henschke, and H.-Liang Wu* "Highly Enantioselective Rh-Catalyzed Alkenylation of Imines: Synthesis of Chiral Allylic Amines via Asymmetric Addition of Potassium Alkenyltrifluoroborates to N-Tosyl IminesOrg. Lett. 201416, 632-635.
    25. H. Kalita, W.-Z. Lee, and M. Ravikanth,* “Synthesis, structure, spectral and electrochemical properties of B(OR)2-smaragdyrin complexesDalton Trans. 2013, 42, 14537-14544.
    26. A. Ghosh, W.-Z. Lee, and M. Ravikanth* "Unusual formation of thiaisoporphyrins from 21-thiaporphyrins"Chem. Commun. 201349, 8677-8679.
    27. H. Kalita, W.-Z. Lee, and M. Ravikanth* "Synthesis and Functionalization of BF2-complexes of meso-free 25-oxasmaragdyrinJ. Org. Chem. 201378, 6285-6290.
    28. A. Ghosh, T. Chatterjee, W.-Z. Lee, and M. Ravikanth* "Unusual Formation of 21-Oxacorrole from 21-Oxaporphyrin Induced by Phosphoryl ChlorideOrg. Lett. 201315, 1040-1043.
    29. W.-Z. Lee,* C.-W. Chiang, G. M. Kulkarni, and T.-S. Kuo “Highly Efficient Proline Ester-Based Catalysts for Michael Addition of Thiophenols to α,β-Enones” J. Chin. Chem. Soc. 2013, 60, 245-250.
    30. B. Gopula, W.-Z. Lee, H.-L. Wu* “Preparation of Chiral α-Substituted Alaninates through an Efficient Diastereoselective Synthesis of Trisubstituted Allylic AlcoholsChem. Asian J. 2013, 8, 80-83.
    31. A. Ghosh, W.-Z. Lee, and M. Ravikanth* "Synthesis, Structure and Properties of a Five-Coordinate Oxophosphorus(V) meso-Triphenylcorrole" Eur. J. Inorg. Chem. 2012, 4231-4239.
    32. W.-Z. Lee,* T.-L. Wang, H.-C. Chang, Y.-T. Chen, and T.-S. Kuo “A Bioinspired ZnII/FeIII Heterobimetallic Catalyst for Thia-Michael AdditionOrganometallics 2012, 31, 4106-4109.
    33. W.-Z. Lee,* C.-W. Chiang, T.-H. Lin, and T.-S. Kuo “A Discrete Five-Coordinate NiIII Complex Resembling the Active Site of the Oxidized Form of Nickel Superoxide DismutaseChem. Eur. J. 2012, 18, 50-53.
    34. W.-Z. Lee,* H.-S. Tsang, T.-L. Wang, H.-L. Tsai,* and T.-S. Kuo “Bio-inspired Catalytic Conjugate Additions of Thiophenols to α,β-Enones by a Disubstituted Benzoate-Bridged Nickel Mimic for the Active Site of UreaseOrganometallics 2010, 29, 2874-2881.
    35. W.-Z. Lee,* T.-L. Wang, H.-S. Tsang, C.-Y. Liu, and C.-T. Chen,* T.-S. Kuo “Temperature Dependant Nuclearity in bis(Benzimidazoyl) Nickel Complexes and Their Catalysis Towards Conjugate Addition of Thiophenols to α,β-EnonesOrganometallics 2009, 28, 652-655.
    36. W.-Z. Lee,* Y.-L. Kang, T.-L. Wang, C.-C. Su,* and T.-S. Kuo “Structural Interconversion Controlled by Hydrogen-bond Interactions: A Mononuclear Copper Triamine Complex and A polynuclear Copper Triamine SheetCryst. Growth Des. 2008, 8, 2614-2616.
    37. W.-Z. Lee,* H.-S. Tseng, M.-Y. Ku, and T.-S. Kuo, “Dinickel Complexes of Disubstituted Benzoate Polydentate Ligands: Mimics for the Active Site of UreaseDalton Trans. 2008, 2538-2541.
    38. C.-T. Chen,* S. Bettigeri, S.-S. Weng, V. Pawar, Y.-H. Lin, C.-Y. Liu, W.-Z. Lee,* “Asymmetric Aerobic Oxidation of  alpha-Hydroxy Acid Derivatives by C4-Symmetric, Vanadate-centered, Tetrakisvanadyl(V) Clusters Derived from N-Salicylidene-alpha-aminocarboxylatesJ. Org. Chem. 2007, 72, 8175-8185.
    39. W.-Z. Lee,* H.-S. Tseng, and T.-S. Kuo, “Ligand-Controlled Nuclearity in Nickel bis(Benzimidazolyl) Complexes” Dalton Trans. 2007, 2563-2570.
    40. C.-H. Hung,* W.-M. Ching, G.-F. Chang, C.-H. Chuang, H.-W. Chu, and W.-Z. Lee, “Formation of a Sulfur-Atom-Inserted N-Confused Porphyrin Iron Nitrosyl Complex by Denitrosation and C-S Bond Cleavage of an S-Nitrosothiol” Inorg. Chem. 2007, 46, 10941-10943.

    41. D. J. Darensbourg, W.-Z. Lee, and L. P. Andrea, “The Synthesis and Characterization of iron cyanide building blocks: [K]2[CpFe(CN)3] and its pentamethylcyclopentadienyl (Cp*) analog” Inorg. Chim. Acta 2005, 358, 4095-4098.

    42. D. J. Darensbourg, W.-Z. Lee, and M. J. Adams, “Phosphine Derivatives of Diamond-Shaped Complexes of Iron(II) and Copper(I) Bridged by Cyanide Groups” Inorganic Syntheses 2004, 34, 172-177.

    43. D. J. Darensbourg,; W.-Z. Lee, A. L. Phelps, and E. Guidry, “Kinetic Study of the Insertion and Deinsertion of Carbon Dioxide into fac-(CO)3(dppe)MnOR Derivatives” Organometallics 2003, 22, 5585-5588.

    44. W.-Z. Lee and W. B. Tolman, “Toward Synthetic Analogs of Linked Redox and Catalytic Multimetal Site in Proteins: A Model of the Histidine-Cysteine Bridged Dicopper Array” Inorg. Chem. 2002, 41, 5656-5658.

    45. D. J. Darensbourg, W.-Z. Lee, and J. C. Yarbrough, “Synthesis and Characterization of a Monocyanide-Bridged Bimetallic Iron(II) and Copper(I) Complex” Inorg. Chem. 2001, 40, 6533-6536.

    46. D. J. Darensbourg, W.-Z. Lee, M. J. Adams, and J. C. Yarbrough, “Diamond-Shaped Heterometallic Complexes of Iron(II) and Copper(I) Bridged by Cyanide Groups Containing Monodentate or Bidentate Phosphanes Bound to Copper(I), Including an Alternative Structure Based on the Nature of the Bidentate Phosphane Ligand” Euro. J. Inorg. Chem. 2001, 2001, 2811-2822.

    47. D. J. Darensbourg, W.-Z. Lee, M. J. Adams, D. L. Larkins, and J. H. Reibenspies, “Diamond-Shaped Heterometallic Complexes of Iron(II) and Copper(I) Bridged by Cyanide Groups” Inorg. Chem. 1999, 38, 1378-1379.

    48. C.-H. Lai, W.-Z. Lee, M. L. Miller, D. J. Darensbourg, and M. Y. Darensbourg, “Responses of the Fe(CN)2(CO) Unit to Electronic Changes as Related to Its Role in [NiFe]Hydrogenase” J. Am. Chem. Soc. 1998, 120, 10103-10114.

    49. D. J. Darensbourg, J. H. Reibenspies, C.-H. Lai, W.-Z. Lee, and M. Y. Darensbourg, “Analysis of an Organometallic Iron Site model for the Heterodimetallic Unit of [NiFe]Hydrogenase” J. Am. Chem. Soc. 1997, 119, 7903-7904.

Unit Title Department Position Date
National Taiwan Normal UniversityProfessorDepartment of Chemistry 2015-02 ~
National Taiwan Normal UniversityDirectorOffice of Research and Development, Instrumentation Center 2012-02 ~ 2013-07
National Taiwan Normal UniversityDirectorOffice of Research and Development, Division of Research Planning and Coordination 2009-08 ~ 2011-07
National Taiwan Normal UniversityAssociate ProfessorDepartment of Chemistry 2009-02 ~ 2015-01
National Taiwan Normal UniversityAssistant ProfessorDepartment of Chemistry 2003-08 ~ 2009-01
University of MinnesotaPostdoctoral FellowDepartment of Chemistry 2001-08 ~ 2003-07
Academic Degrees
School Nation Department Degree Date
Texas A&M UniversityU.S.Department of ChemistryPh.D.1997-01 ~ 2001-06
National Chang hua University of EducationTaiwanDepartment of ChemistryB.S.1988-09 ~ 1992-06
Awarded Year Award Arwarding Unit
2013Teaching AwardNational Taiwan Normal University
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  1. Journal papers
  2. Conference papers
  3. Research projects