姓名 陳頌方
實驗室電話 (02)7734-6210
辦公室電話 (02)7734-6180
傳真 (02)2932-4249
聯絡地址 (11677) 台北市文山區汀州路四段88號
E-mail sfchen@ntnu.edu.tw
類別 專任師資
職稱 教授
研究領域 分析化學、生化質譜分析、層析分離
指導學生 葉沛柔,林怡青,楊皓閔,朱仕麒,謝磊,黃于娟
實驗室 生化質譜研究室 /


  1. 期刊論文
    1. Ting-Ting Yeh, Ming-Yi Ho, Wei-Ya Chen, Ya-Chen Hsu, Wei-Chi Ku, Hsiang-Wen Tseng, Shih-Ta Chen, Sung-Fang Chen. Comparison of different fractionation strategies for in-depth phosphoproteomics by liquid chromatography tandem mass spectrometry. (2019) Analytical and Bioanalytical Chemistry (in print)
    2. Shi-Han Jian, Pei-Jou Yeh,, Chung-Huang Wang, Hsin-Chang Chen, Sung-Fang Chen. Analysis of heterocyclic amines in meat products by liquid chromatography - Tandem mass spectrometry. (Apr, 2019) Journal of Food and Drug Analysis. 2019, 27(2): 292-602.
    3. Sheng-Yu Huang, Tin-Yu Wei, Bing-Shin Liu, Min-Han Liu, Sheng-Kuo Chiang, Sung-Fang Chen*, Wang-Chou Sung*. Monitoring the Disulfide Bonds of Folding Isomers of Synthetic CTX A3 Polypeptide Using MS-Based Technology. (Jan, 2019) Toxins, 2019, 17;11(1): 52
    4. Yi-Li Huang, Bing-Yi Jhou, Sung-Fang Chen,* Kay-Hooi Khoo*. Identifying Specific and Differentially Linked Glycosyl Residues in Mammalian Glycans by Targeted LC-MS. (Aug, 2018) Analytical Sciences, 2018, 34(9):1049-1054.
    5. Pei-Lun Tsai, Tsu-Yi Sung, Chinh-Yen Chong, Sheng-Yu Huang, Sung-Fang Chen*. Comparison of Poly(Styrene-Divinylbenzene)-based Monolithic and Bead-based Methodologies Used in NANOFLOW LCMS for Proteomic Studies. (Aug, 2018), Analytical Methods, 2018, 10, 4756-4764.
    6. Ching-Hsin Tung, Chih-Chieh Lin, Ching-Chuan Tung, Sung-Fang Chen, Fuu Sheu, Ting-Jang Lu*. Combination of on-line desalting and HPLC-UVESI-MS for simultaneous detection and identification of FIP-fve and flammutoxin in Flammulina velutipes. (Jul, 2018), Journal of Food and Drug Analysis, 2018;26(3):1045-53.
    7. Ching-Hsin Tung, Chih-Chieh Lin, Huei-Ju Wang, Sung-Fang Chen, Fuu Sheu, Ting-Jang Lu*. Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein, FIP-fve, extract from Flammulina velutipes. (Jul, 2018), Journal of Food and Drug Analysis, 2018;26(3):1005-14
    8. Shih-Chieh Lu, Wan-Rou Liao, Sung-Fang Chen*. Quantification of trans-resveratrol in red wines using QuEChERS extraction combined with liquid chromatography - tandem mass spectrometry. (Apr, 2018), Analytical Sciences, 2018;34(4):439-444
    9. Pei-Lun Tsai, Sung-Fang Chen*. Bioinformatics Tools for Glycosylation Analysis by Mass Spectrometry. (Feb, 2017), Mass Spectrometry (Tokyo), 6, 2, S0064
    10. Huang-Joe Wang, Sung-Fang Chen,* Wan-Yu Lo*. Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics. (Oct, 2016), Scientific Reports, 2018;6:35372
    11. Wang-Chou Sung, Chiung-Wen Chang, Sheng Yu Huang, Ting-Yu Wei, Yi-Li Huang, Yu-Hua Lin, Han-Min Chen, Sung-Fang Chen*. Evaluation of disulfide scrambling during the enzymatic digestion of bevacizumab at various pH values using mass spectrometry. BBA - Proteins and Proteomics, 1864:9, 1188-94, 2016
    12. Yi-Fang Cheng, Guang-Huar Young, Tsu-Man Chiu, Jiun-Tsai Lin, Pei-Ru Huang, Cheng-Yi Kuo, Yao-Jen Liang, Po-Ku Chen, Sung-Fang Chen, Ching-Yi Cheng, Han-Min Chen*. Adenine supplement delays senescence in cultured human follicle dermal papilla cells. Experimental Dermatology, 25:2, 162-4, 2016
    13. Kung-Hao Liang, Chih-Lang Lin, Sung-Fang Chen, Chih-Wei Chiu, Pei-Ching Yang, Ming-Ling Chang, Chen-Chun Lin, Kai-Feng Sung, Cassandra Yeh, Chien-Fu Hung, Rong-Nan Chien, Chau-Ting Yeh*. GALNT14 genotype effectively predicts the therapeutic response in unresectable hepatocellular carcinoma treated with transcatheter arterial chemoembolization. Pharmacogenomics, 17:4, 353-66, 2016
    14. Chih-Wei Chiu, Han-Min Chen, Tzong-Ta Wu, Ying-Chu Shih, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ling Hsu, Sung-Fang Chen*. Differential Proteomics of Monosodium Urate Crystals-Induced Inflammatory Response in Dissected Murine Air Pouch Membranes by iTRAQ Technology. Proteomics, 15:19, 3338-48, 2015
    15. Chih-Wei Chiu, Sung-Fang Chen*. Peptide Fractionation by Multidimensional Liquid-based Separation Techniques for Proteomic Analysis. CHEMISTRY (The Chinese Chemical Society, Taipei), 73:1, 57-66, 2015
    16. Huang-Joe Wang, Sung-Fang Chen*, Wan-Yu Lo*. iTRAQ quantitative proteomics-based identification of cell adhesion as a dominant phenotypic modulation in thrombin-stimulated human aortic endothelial cells. Thrombosis Research, 135:5, 944-50, 2015
    17. Yi-Ting Chen, Li-Ping Tuan, Hsiao-Wei Chen, I-An Wei, Min-Yuan Chou, Han-Min Chen, Yu-Chang Tyan, Sung-Fang Chen*. Quantitative Analysis of Prostate Specific Antigen Isoforms Using Immunoprecipitation and Stable Isotope Labeling Mass Spectrometry. Analytical Chemistry, 87:1, 545-553, 2015
    18. Sheng-Yu Huang, Sung-Fang Chen, Chun-Hao Chen, Hsuan-Wei Huang, Wen-Guey Wu, Wang-Chou Sung*. Global Disulfide Bond Profiling for Crude Snake Venom Using Dimethyl Labeling Coupled with Mass Spectrometry and RADAR Algorithm. Analytical Chemistry, 86:17, 8742–8750, 2014
    19. Pei-Lun Tsai, Sung-Fang Chen, Sheng-Yu Huang*. Mass Spectrometry based strategies for protein disulfide bond identification. Reviews in Analytical Chemistry, 32:4, 257-268, 2014
    20. Ching-Huai Ko, Chieh-Fang Cheng, Chin-Pen Lai, Te-Hui Tzu, Chih-Wei Chiu, Mei-Wei Lin, Si-Yuan Wu, Chung-Yuan Sun, Hsiang-Wen Tseng, Chun-Chung Wang, Zong-Keng Kuo, Ling-Mei Wang, Sung-Fang Chen*. Differential Proteomic Analysis of Cancer Stem Cell Properties in Hepatocellular Carcinomas by Isobaric Tag Labeling and Mass Spectrometry. Journal of Proteome Research, 12:8, 3573–3585, 2013
    21. Yu-Hung Su, Yen-Ling Lee, Sung-Fang Chen, Yun-Ping Lee, Yi-Hsuan Hsieh, Jui-He Tsai, Jye-Lin Hsu, Wei-Ting Tian, Wenya Huang*. Essential role of β-human 8-oxoguanine DNA glycosylase 1 in mitochondrial oxidative DNA repair. Environ Mol Mutagen, 54:54-64, 2013
    22. Chih-Wei Chiu, Chun-Lun Chang, Sung-Fang Chen*. Evaluation of peptide fractionation strategies used in proteome analysis. Journal of Separation Science, 35:23, 3293-3301, 2012
    23. Wan-Yu Lo, Huang-Joe Wang, Chih-Wei Chiu, Sung-Fang Chen*. miR-27b-Regulated TCTP as a Novel Plasma Biomarker for Oral Cancer: From Quantitative Proteomics to Post-Transcriptional Study. Journal of Proteomics, 77, 154-166, 2012
    24. Sheng-Yu Huang, Yu-Ting Hsieh, Chun-Hao Chen, Chao-Chi Chen, Wang-Chou Sung, Min-Yuan Chou, Sung-Fang Chen*. Automatic Disulfide Bond Assignment Using a1 Ion Screening by Mass Spectrometry for Structural Characterization of Protein Pharmaceuticals. Analytical Chemistry, 84:11, 4900-4906, 2012
    25. Yuan-Feng Lin, Tien-Shun Yeh, Sung-Fang Chen, Yu-Hui Tsai*, Chih-Ming Chou, Yi-Yuan Yang, Haw-Ming Huang. Nonmuscle myosin IIA (myosin heavy polypeptide 9): a novel class of transducer mediating the activation of G alpha h/phospholipase C- delta 1 pathway. Endocrinology, 151:3, 876-885, 2010
    26. Hung-Yu Sun, Sung-Fang Chen, Ming-Derg Lai, Ting-Tsung Chang, Tz-Li Chen, Pei-Yu Li, Dar-Bin Shieh, Kung-Chia Young*. Comparative proteomic profiling of plasma very-low-density and low-density lipoproteins. Clinica Chimica Acta, 411, 336-344, 2010
    27. Hui-Chu Hsieh, Yi-Ting Chen, Jen-Ming Li, Ting-Yu Chou, Ming-Fong Chang, See-Chang Huang, Tzu-Ling Tseng, Chung-Cheng Liu, Sung-Fang Chen*. Protein Profilings in Mouse Liver Regeneration after Partial Hepatectomy using iTRAQ Technology. Journal of Proteome Research, 8:2, 1004-1013, 2009
    28. Yu-Wei Wu, Sung-Fang Chen, Charng-Bin Yang, Yu-Hui Tsai. Screening, purification, and identification of a copper-dependent FITC-binding protein in human plasma: Albumin. Journal of Chromatography B, 863:187–191, 2008
    29. Ying-Fang Yang*, Min-Yuan Chou, Chia-Yu Fan, Sung-Fang Chen, Ping-Chiang Lyu, Chung-Cheng Liu, Tzu-Ling Tseng. The possible interaction of CDA14 and protein elongation factor 1α. Biochimica et Biophysica Acta, 1784:312–318, 2008
    30. Sung-Fang Chen*, Pei-Yu Li, Hui-Ju Shen. Powerful tools for biomarker discovery: An overview of differential proteomics. CHEMISTRY (The Chinese Chemical Society, Taipei), 65:2, 211-224, 2007 (Invited review paper)
    31. Chia-Hsin Chan, Chia-Cheng Ko, Jan-Gowth Chang, Sung-Fang Chen, Ming-Shiang Wu, Jaw-Town Lin, Lu-Ping Chow*. Subcellular and Functional Proteomic Analysis of the Cellular Responses Induced by Helicobacter pylori. Molecular & Cellular Proteomics, 5:702-713, 2006
    32. Hsiu-Chuan Li, Chuan-Chuan Huang, Sung-Fang Chen, Min-Yuan Chou*. Assembly of homotrimeric type XXI minicollagen by coexpression of prolyl 4-hydroxylase in stably transfected Drosophila melanogaster S2 cells. Biochemical and Biophysical Research Communications, 336, 375-385, 2005
    33. Tzann-Shun Hwang, Chih-Hung Hung, Chin-Fen Teo, Guan-Ting Chen, Lee-Shang Chang, Sung-Fang Chen, Yu-Ju Chen*, Chun-Hung Lin*. Structural Characterization of Escherichia coli Sialic Acid Synthase. Biochemical and Biophysical Research Communications, 295, 167-173, 2002
    34. Sung-fang Chen, Michael PC Ip, Yan Xu*. Electrochemical enzyme immunoassay for serum prostate-specific antigen at low concentrations. Clinical Chemistry, 43: 1459-1461, 1997