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個人詳細資料

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˹ʹϤ
姓名 姚清發
Office_Hour  
實驗室電話 (02)77346156
辦公室電話 (02)77346128
傳真 (02)29324249
聯絡地址 (11677)台北市文山區汀州路四段88號
E-mail cheyaocf@ntnu.edu.tw
實驗室網頁 http://www.chem.ntnu.edu.tw/~cheyaocf/Yao
類別 專任師資
職稱 教授
研究領域 物理有機化學、有機合成
學術專長 研究興趣
探討β-硝基苯乙烯和各種試劑之反應機構和開發新的合成方法


指導學生  
實驗室 物理有機研究室 /

學術著作

  1. 期刊論文
    1. 135. Chang, K.-H.; Lin, C.-H.; Chen, H.-C.; Huang, H.-Y.; Chen, S.-L.; Lin, T.-H.; Ramesh, C.; Huang, C.-C.; Fung, H.-C.; Wu, Y.-R.; Huang, H.-J.; Lee-Chen, G. J.*; Hsieh-Li, H. M.*; Yao, C.-F.* CNS Neuroscience & Therapeutics 2016, 22(x), xxxx-xxxx. (x) (Pharmacology & Pharmacy: 42/253 or Neuroscience: 65/256, 2015 IF: 4.018; 5 year impact factor: 4.089) Online ISSN: 1755-5930

      The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1          

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      134. Liu, C.-Y.; Hsieh, C.-H.; Kim, S.-H.; Wang, J.-P.; Ni, Y.-L.; Su, C.-L.; Yao, C.-F.; Fang, K.* International Journal of Oncology 2016, 49 (xx), 2031-2041. (x) (Oncology: 100/213, 2015 IF: 3.018; 5 year impact factor: 2.990) Online ISSN: 1791-2423

      An indolylquinoline derivatives activates DNA damage resoponse and apotosis in human hepatocellular carcinoma cells

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      133. Huang, C.-Y.; Kuo, C.-W.; Konala, A.; Yang, T.-H.; Lin, L.; Chen, Y.-.; Kavala, V.; Yao, C.-F.* RSC Adv. 2016, 6 (98), 96049-96056. (10) (Chemistry, Multidisciplinary: 49/163, 2015 IF: 3.289; 5 year impact factor: 3.485) Online ISSN: 2046-2069

      Synthesis of 3-arylindole derivatives from nitroalkane precursors

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      132. Chang, H. H.; Lee, L.-H.; Leong, W.-Y.; Yang, T.-C.; Yao, C.-F.; Fang, K.* Drug Design, Development and Therapy 2016, 10, 2947-2957. (9) (Pharmacology & Pharmacy 84/255, 2014 IF: 2.881; 5 year impact factor: 2.962) Online ISSN: 1177-8881

      A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      131. Villuri, B. K.; Kotipalli, T.; Kavala, V.; Ichake, S. S.; Bandi, V. ; Kuo, C.-W.; Yao, C.-F.* RSC Adv. 2016, 6 (78), 74845-74858. (8) (Chemistry, Multidisciplinary: 49/163, 2015 IF: 3.289; 5 year impact factor: 3.485) Online ISSN: 2046-2069

      Synthesis of Spiro Isoindolinone-indolines and 1,2-Disubstituted Indoles from 2-Iodobenzamide Derivatives 

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      130. Kotipalli, T.;  Kavala, V.; Ashok konala, A.;  Janreddy, D.; Kuo, C.-W.; Yao, C.-F.* Adv. Synth. Catal. 2016, 358(16), 2652-2660. (8) (Applied Chemistry: 1/72 or Organic Chemistry: 5/59, 2015 IF: 6.453; 5 year impact factor: 5.852) Online ISSN: 1615-4169 (Times Cited: 1)

      Reagent/Substituent Switching Approach for the Synthesis of Substituted 1,3,4-Oxadiazole/1,3,4-Oxadiazoline and 1,2,4-Triazole Derivatives from N-Substituted Hydrazides

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      129. Kuo, C.-W.; Konala, A.; Lin, L.; Chiang, T.-T.; Huang, C-Y.; Yang, T-H .; Kavala, V.; Yao, C.-F* Chem. Commun. 2016, 52(50), 7870-7873. (6) (Chemistry, Multidisciplinary: 21/163, 2015 IF: 6.567; 5 year impact factor:6.628) Online ISSN: 1359-7345

      Synthesis of Benzo[a]carbazole derivatives from 3-Ethylindoles by Exploiting the Dual Character of Benzoquinone as an oxidizing agent and Dienophile

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      128. Huang, C.-Y.; Kuo, C.-W.; Kavala, V.; Yao, C.-F* Eur. J. Org. Chem. 2016, (15), 2720-2734. (5) (Organic Chemistry: 17/59, 2015 IF: 3.068; 5 year impact factor:2.971) Online ISSN: 1099-0690

      Syntheses of 2-benzylbenzofuran derivatives and 2-arylnitrochroman derivatives from nitroalkene precursors

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      127. Kotipalli, T.; Kavala, V.; Janreddy, D.; Bandi, V.; Kuo, C.-W.; Yao, C.-F*

      Eur. J. Org. Chem. 2016, (6), 1182-1193. (2) (Organic Chemistry: 17/59, 2015 IF: 3.068; 5 year impact factor: 2.971) Online ISSN: 1099-0690 (Times Cited:2)

      Synthesis of 2,3-Disubstituted Quinazolinone Derivatives Through Copper Catalyzed C–H Amidation Reactions

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      126. Ichake, S. S.; Rajawinslin, R. R.; Kavala, V.; Villuri, B. K.; Yang, H.-T.; Kuo, C.-W.; Yao, C.-F.* Asian J. Org. Chem. 2016, 5(3), 343-352. (3) (Organic Chemistry: 16/59, 2015 IF: 3.275; 5 year impact factor: 3.296) Online ISSN: 2193-5815 (Times Cited: 0)

      NBS Mediated Thiocyanation of Cyclohexene Fused Isoxazoline N-Oxides

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      125. Chang, K. H.; Chiu, Y. J.; Chen, S. L.; Huang, C. H.; Lin, C. H.; Lin, T. H.; Lee, C. M.; Ramesh, C.; Wu, C. H., Huang, C. C.; Fung, H. C.; Chen, Y. C.; Lin, J. Y.; Yao, C. F.; Huang, H. J.; Lee-Chen, G. J.*; Lee, M. C.*; Hsieh-Li, H. M.* Neuropharmacology 2016, 101, 309-319. (2) (Field of Pharmacology & Pharmacy: 19/253, 2015 IF:4.936; 5 year impact factor: 4.709) Online ISSN 0028-3908 (Times Cited: 1)

      The potential of synthetic indolylquinoline derivatives for Aβ aggregation reduction by chemical chaperone activity

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      124. Liu,C.-Y.; Wu, P.-T.; Wang, J.-P.; Fan, P.-W.; Hsieh, C.-H.; Su, C.; Chiu, C.-C.; Yao, C.-F.; Fang, K.* Apoptosis 2015, 20(11), 1471-1482. (12) (Field of Biochemistry & Molecular Biology: 93/289 or Cell Biology: 80/180, 2014 IF:3.592; 5 year impact factor: 3.617) ISSN: 1360-8185 (Print) 1573-675X (Online) (Times Cited: 3)

      An indolylquinoline derivative promotes apoptosis in human lung cancer cells by impairing mitochondrial functions

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      123. Chen, W.-C.: Lin, C.-C.; Kavala, V.; Kuo, C.-W.; Huang, C.-Y.; Yao, C.-F.* Molecules 2015, 20(12), 22419-22519. (12) (Organic Chemistry: 24/59, 2015 IF: 2.465; 5 year impact factor: 2.749) Online ISSN 1420-3049 (Times Cited: 0)

      Syntheses of 4-Indolylquinoline Derivatives via Reductive Cyclization of Indolylnitrochalcone Derivatives by Fe/HCl

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      122. Rajawinslin, R. R.; Gawande, S. D.; Kavala, V.; Huang, Y.-H. ; Kuo, C.-W.; Kuo, T.-S.; Chen, M.-L.; He, C.-H.; Yao, C.-F.* RSC Adv., 2015, 5 (64), 52141-52153. (7) (Chemistry, Multidisciplinary: 48/163, 2015 IF: 3.289; 5 year impact factor: 3.485) Online ISSN: 2046-2069 (Times Cited: 2)

      Iron/acetic acid mediated synthesis of 6,7-dihydrodibenzo [b,j] [1,7] phenanthroline derivatives via intramolecular reductive cylization

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      121. Chen, W.-C.: Kavala, V.; Shih, Y.-H.; Wang, Y.-H.; Kuo, C.-W.; Yang, T.-H.; Huang, C.-Y.; Chiu, H,-H.; Yao, C.-F.* Molecules 2015, 20(6), 10910-10927. (6) (Organic Chemistry: 24/59, 2015 IF: 2.465; 5 year impact factor: 2.749) Online ISSN 1420-3049 (Times Cited: 1)

      Synthesis of Bicyclic Isoxazoles and Isoxazolines via Intramolecular Nitrile Oxide Cycloaddition

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      120. Gawande, S. D.; Zanwar, M. R.; Kavala, V.; Kuo, C.-W.; Yao, C.-F.* Adv. Synth. Catal. 2015, 375(1), 168-175. (1) (Applied Chemistry: 1/71 or Organic Chemistry: 5/59, 2015 IF: 6.453; 5 year impact factor: 5.852) Online ISSN: 1615-4169 (Times Cited: 2)

      One Pot Synthesis of 2-Arylquinaloine and Tetracyclic-Isoindolo[1,2-a]quinazoline Derivatives via Cyanation Followed by the Rearrangement of o-Substituted 2-Halo-N-Arylbenzamides

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      119. Meesala, Y.; Kavala, V.; Chang , H.-C.; Kuo, T.-S.; Yao, C.-F.*; Lee, W.-Z.* Dalton Trans. 2015, 44(3), 1120-1129. (1) (Inorganic & Nuclear Chemistry: 6/45, 2015 IF: 4.177; 5 year impact factor: 4.003) Online ISSN: 1477-9226 (Times Cited: 6)

      Synthesis, structures and electrochemical and photophysical properties of anilido-benzoxazole boron difluoride (ABB) complexes

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      118. Zanwar, M. R.; Gawande, S. D.; Kavala, V.; Kuo, C.-W.; Yao, C.-F.* Adv. Synth. Catal. 2014, 356(18), 3849-3860. (12) (Applied Chemistry: 2/71 or Organic Chemistry: 5/58, 2013 IF: 5.542) Online ISSN: 1615-4169 (Times Cited: 3)

      Iron(III)chloride Catalyzed Synthesis of Highly Substituted Indolyl-Tetrahydroquinoline Derivatives by Using Electron Deficient Dienophiles and Its Application to the Synthesis of Indolo-Benzonaphthyridine Derivatives

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      117. Lin, C.-H.; Wu, Y.-R.; Kung, P.-J.; Chen, W.-L.; Lee, L.-C.; Lin, T.-H.; Chao, C.-Y.; Chen, C.-M.; Chang, K.-H.; Janreddy, D.; Lee-Chen, G.-J.*; Yao, C.-F.* ACS Chem. Neurosci., 2014, 5(10), 1063-1074. (10)  ISSN: 1948-7193 (Times Cited: 2) (Neuroscience: 65/251, 2013 IF: 4.210) published online September 8, 2014

      The Potential of Indole and a Synthetic Derivative for PolyQ Aggregation Reduction by Enhancement of the Chaperone and Autophagy Systems

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      116. Kung, P.-J.; Tao, Y.-C.; Hsu, H.-C.; Chen, W.-L.; Lin, T.-H.; Janreddy, D.; Yao, C.-F.; Cahng, K.-H.; Lin, J.-Y.; Su, M.-T.; Wu, C.-H.; Lee-Chen, G.-J.*; Hsieh-Li, H.-M.* Drug Design, Development and Therapy 2014, 8, 1929-1939. (10) (Pharmacology & Pharmacy 76/254, 2014 IF: 3.03) Online ISSN: 1177-8881 (Times Cited: 2)

      Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      115. Kotipalli, T.; Janreddy, D.; Kavala, V.; Kuo, C.-W.; Kuo, T.-S.; Chen, M.-L.; He, C.-H.; Yao, C.-F.* RSC Adv., 2014, 4(88), 47833-47840. (10) (Chemistry, Multidisciplinary: 35/148, 2013 IF:  3.840; 5 year impact factor: 3.907) Online ISSN: 2046-2069 (Times Cited: 0)

      BF3•OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation

      計畫編號: NSC-100-2113-M-003-008-MY3

       

      114. Janreddy, D.; Kavala, V.; Kotipalli, T.; Kuo, C.-W.; Kuo, T.-S.; Chen, M.-L.; He, C.-H.; Yao, C.-F.* Adv. Synth. Catal. 2014, 356(14-15), 3083-3091. (10) (Applied Chemistry: 2/71 or Organic Chemistry: 5/58, 2013 IF: 5.542) Online ISSN: 1615-4169  (Times Cited: 0)

      Palladium(II)Chloride Catalyzed Aerobic Oxidative Intermolecular [4+2] Cycloaddition Reaction of 2-Alkynyl Benzaldehydes and Electron-Deficient Terminal Alkenes: An Efficient Synthesis of Naphthyl ketones

      計畫編號: NSC-100-2113-M-003-008-MY3

      Kavala, V.; Wang, C.-C.; Barange, D. K.; Kuo, C.-W.; Lei, P.-M.; Yao, C.-F.* J. Org. Chem. 2012, 77(11), 5022-5029. (6) (Organic Chemistry: 10/57, 2012 IF: 4.564) Online ISSN: 1520-6904 (Times Cited: 42)

      Synthesis of Isocoumarin Derivatives via the Copper-Catalyzed Tandem Sequential Cyclization of 2- Halo-N-phenyl Benzamides and Acyclic 1,3-Diketones

      計畫編號: NSC-100-2113-M-003-008-MY3

      經歷一覽
      服務機關 職稱 部門/系所 擔任職務 起迄年月
      國立臺灣師範大學教授化學系特聘教授2014年01月 ~ 2019年12月
      國立臺灣師範大學教授化學系優聘教授2013年01月 ~ 2013年12月
      國立臺灣師範大學教授化學系兼任教育部國民中小學課程與教學輔導組自然與生活科技學習領域召集人2012年08月 ~
      國立臺灣師範大學主任化學系系所主任2010年08月 ~ 2012年07月
      美國愛荷華州立大學訪問學者化學系訪問學者2006年08月 ~ 2007年07月
      國立臺灣師範大學教授化學系 1999年08月 ~
      國立臺灣師範大學副教授化學系 1993年08月 ~ 1999年07月
      美國愛荷華州立大學博士後研究化學系博士後研究員1993年06月 ~ 1993年07月
      美國喬治亞理工學院博士後研究化學系博士後研究員1992年09月 ~ 1993年05月
      美國愛荷華州立大學博士後研究化學系博士後研究員1991年05月 ~ 1992年08月
      美國愛荷華州立大學 化學系博士班研究生1986年07月 ~ 1991年05月
      國立臺灣師範大學助教化學系 1985年08月 ~ 1986年07月
      服兵役少尉預官  1983年07月 ~ 1985年05月
      台北縣立淡水國民中學教師  1982年08月 ~ 1983年07月
學歷一覽
學校名稱 國別 系所 學位 起迄年月
愛荷華州立大學美國化學系博士1986年08月 ~ 1991年05月
國立臺灣師範大學臺灣化學系理學士1978年09月 ~ 1983年06月
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  1. 期刊論文
  2. 學術研究計畫
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