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學術成果

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學術著作
類型 著作 著作人
期刊論文Chen, Y.-R.; Reddy, G. M.; Hsieh, K.-H.; Chen, K.-H.; Karanam, P.; Vagh, S. S.; Liou, Y.-C.; Lin, W.* "3-Homoacyl Coumarins as a Class of All-Carbon 1,3-Dipole Precursors: An Enantioselective Concerted (3+2) Cycloaddition towards Coumarin/Indandione-Fused Spirocyclopentanes" Chem. Commun. 2018accepted.林文偉
期刊論文"Identification of Stabilizing High-valent Active Sites by Operando High-energy Resolution Fluorescence-detected X-ray Absorption Spectroscopy for High Efficient Water Oxidation", 
Sung-Fu Hung,+ Yu-Te Chan (詹佑得),+ Chun-Chih Chang (張鈞智), Ming-Kang Tsai,* Yen-Fa Liao, Nozomu Hi
raoka, Chia-Shuo Hsu, Hao Ming Chen,* 2018 (submitted).
 [+ denotes equal contribution]
蔡明剛
期刊論文 杜玲嫻
期刊論文  

1.    Ling-Hsien Tu, Ning-Hsuan Tseng, Ya-Ru Tsai, Tien-Wei Lin, Yi-Wei Lo, Jien-Lin Charng, Hua-Ting Hsu, Yu-Sheng Chen, Rong-Jie Chen, Ying-Ta Wu, Yi-Tsu Chan, Chang-Shi Chen, Jim-Min Fang,* and Yun-Ru Chen* (2018, Oct). Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity. European Journal of Medicinal Chemistry, 158, 393-404

 

2.    Arnaldo Serrano, Justin Lomont, Ling-Hsien Tu, Daniel Raleigh,and Martin Zanni* (2017, Oct). A free energy barrier caused by the refolding of an oligomeric intermediate controls the lag time of amyloid formation by hIAPP. Journal of the American Chemical Society, 139(46), pp 16748–16758. 
 

3.    Lydia M. Young, Ling-Hsien Tu, Daniel P. Raleigh, Alison E. Ashcroft and Sheena E. Radford* (2017, May). Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science, 8(7), 5030-5040.
 

4.    Andisheh Abedini*, Annette Plesner, Ping Cao, Zachary Ridgway,Jinghua Zhang, Ling-Hsien Tu, Chris T Middleton, Brian Chao,Daniel J Sartori, Fanling Meng, Hui Wang, Amy G Wong, Martin T Zanni,C Bruce Verchere, Daniel P Raleigh*, Ann Marie Schmidt* (2016, May). Time-resolved studies define the nature of toxic IAPP intermediates, providing nsight for anti-amyloidosis therapeutics. eLIFE, 5:e12977. 
 

5.    Rehana Akter, Ping Cao, Harris Noor, Zachary Ridgway, Ling-Hsien Tu, HuiWang, Amy G.Wong, Xiaoxue Zhang, Andisheh Abedini, AnnMarie Schmidt, and Daniel P. Raleigh* (2016). Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology. Journal of Diabetes Research, Article ID 2798269. 
 

6.    Daniel T. Meier, Ling-Hsien Tu, Sakeneh Zraika, Meghan F. Hogan, Andrew T. Templin, Rebecca L. Hull, Daniel P. Raleigh, and Steven E. Kahn* (2015, Dec). Matrix Metalloproteinase-9 Protects Islets from Amyloid induced Toxicity. Journal of Biological Chemistry, 290(51), 30475–30485. co-first author

7.      Lydia M. Young, Rachel A. Mahood, Janet C. Saunders, Ling-Hsien Tu, Daniel P. Raleigh, Sheena E. Radford* and Alison E. Ashcroft* (2015, Oct). Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry. Analyst, 140, 6990–6999. 
 

8.    Ling-Hsien Tu, Lydia M. Young, Amy G. Wong, Alison E. Ashcroft, Sheena E. Radford, and Daniel P. Raleigh* (2015, Jan). Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic−Inhibitor and Histidine−Inhibitor Interactions. Biochemistry, 54, 666-676. 
 

9.    Lydia M. Young, Janet C. Saunders, Rachel A. Mahood, Charlotte H. Revill1,Richard J. Foster, Ling-Hsien Tu, Daniel P. Raleigh, Sheena E. Radford* and Alison E. Ashcroft* (2015, Jan). Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry. Nature Chemistry, 7, 73-81. 

10.  Ling-Hsien Tu, Harris Noor, Ping Cao, and Daniel P. Raleigh* (2014, May). Aspirin, Diabetes, and Amyloid: Re-examination of the Inhibition of Amyloid Formation by Aspirin and Ketoprofen. ACS Chemical Biology, 9, 1632-1637.
 

11.  Ling-Hsien Tu, Arnaldo L. Serrano, Martin T. Zanni, and Daniel P. Raleigh* (2014, Apr). Mutational Analysis of Preamyloid Intermediates: The Role of His-Tyr Interactions in Islet Amyloid Formation. Biophysical Journal , 106, 1520-1527.  
 

12.  Ping Cao, Andisheh Abedini, Hui Wang, Ling-Hsien Tu, Xiaoxue Zhang, Ann Marie Schmidt,and Daniel P. Raleigh* (2013, Nov). Islet amyloid polypeptide toxicity and membrane interactions. Proceedings of the National Academy of Sciences, 110(48), 19279–19284. 
 

13.  Ping Cao, Peter Marek, Harris Noor, Vadim Patsalo, Ling-Hsien Tu, Hui Wang, Andisheh Abedini,Daniel P. Raleigh* (2013, Apr). Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity. FEBS Letter, 587, 1106–1118. 
 

14.  Ling-Hsien Tu and Daniel P. Raleigh* (2013, Jan). Role of Aromatic Interactions in Amyloid Formation by Islet Amyloid Polypeptide. Biochemistry, 52, 333-342. 
 

15.  Ping Cao, Ling-Hsien Tu, Andisheh Abedini, Olesya Levsh, Rehana Akter, Vadim Patsalo, Ann Marie Schmidt and Daniel P. Raleigh* (2012, Aug). Sensitivity of Amyloid Formation by Human Islet Amyloid Polypeptide to Mutations at Residue 20. Journal of Molecular Biology, 421, 282–295. 
 

16.  Ming-Chang P. Yeh,* Wei-Jou Yeh, Ling-Hsien Tu and Jia-Ru Wu (2006, Jun). CeCl3.7H2O–NaI catalyzed intramolecular addition reactions of 7-hydroxy-1,3-dienes: a facile approach to hexahydrobenzofurans and tetrahydrofurans. Tetrahedron, 62, 7466–7470. 
 

17.  Ming-Chang P. Yeh,* Wen-Cheng Tsao, and Ling-Hsien Tu (2005, Oct). Palladium-Catalyzed Reaction of Aryl Bromides with 7-Hydroxy-1,3-Dienes. Organometallics, 24, 5909-5915. 
 

18.  Ming-Chang P. Yeh,* Wen-Cheng Tsao, Jin-Shen Ho, Chih-Chuan Tai,Dai-Yu Chiou, and Ling-Hsien Tu (2004, Jan). Rhodium(I)-Catalyzed Intramolecular Cyclohexadienyl Pauson-Khand Reaction: Facile Approach to Tricarbocycles. Organometallics, 23, 792-799. 

 

杜玲嫻
期刊論文Lee, S.-Y.; Chiu, Y.-J.; Yang, S.-M.; Chen, C.-M.; Huang, C.-C.; Lee-Chen, G.-J.*; Lin, W.*; Chang, K.-H.* "Novel Synthetic Chalcone–coumarin Hybrid for Aβ Aggregation Reduction, Antioxidation, and Neuroprotection" CNS Neurosci. Ther. 2018accepted.林文偉
期刊論文Pei-Lun Tsai, Tsu-Yi Sung, Chinh-Yen Chong, Sheng-Yu Huang, Sung-Fang Chen*. Comparison of Poly(Styrene-Divinylbenzene)-based Monolithic and Bead-based Methodologies Used in NANOFLOW LCMS for Proteomic Studies. (Aug, 2018), Analytical Methods, 2018, Accepted.陳頌方
期刊論文Yi-Li Huang, Bing-Yi Jhou, Sung-Fang Chen,* Kay-Hooi Khoo*. Identifying Specific and Differentially Linked Glycosyl Residues in Mammalian Glycans by Targeted LC-MS. (Aug, 2018) Analytical Sciences, 2018, Accepted. 陳頌方
期刊論文Ching-Hsin Tung, Chih-Chieh Lin, Ching-Chuan Tung, Sung-Fang Chen, Fuu Sheu, Ting-Jang Lu*. Combination of on-line desalting and HPLC-UVESI-MS for simultaneous detection and identification of FIP-fve and flammutoxin in Flammulina velutipes. (Jul, 2018), Journal of Food and Drug Analysis, 2018;26(3):1045-53. 陳頌方
期刊論文Ching-Hsin Tung, Chih-Chieh Lin, Huei-Ju Wang, Sung-Fang Chen, Fuu Sheu, Ting-Jang Lu*. Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein, FIP-fve, extract from Flammulina velutipes. (Jul, 2018), Journal of Food and Drug Analysis, 2018;26(3):1005-14 陳頌方
期刊論文Shih-Chieh Lu, Wan-Rou Liao, Sung-Fang Chen*. Quantification of trans-resveratrol in red wines using QuEChERS extraction combined with liquid chromatography - tandem mass spectrometry. (Apr, 2018), Analytical Sciences, 2018;34(4):439-444陳頌方
期刊論文Pei-Lun Tsai, Sung-Fang Chen*. Bioinformatics Tools for Glycosylation Analysis by Mass Spectrometry. (Feb, 2017), Mass Spectrometry (Tokyo), 6, 2, S0064陳頌方
期刊論文Huang-Joe Wang, Sung-Fang Chen,* Wan-Yu Lo*. Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics. (Oct, 2016), Scientific Reports, 2018;6:35372陳頌方
期刊論文Wang-Chou Sung, Chiung-Wen Chang, Sheng Yu Huang, Ting-Yu Wei, Yi-Li Huang, Yu-Hua Lin, Han-Min Chen, Sung-Fang Chen*. Evaluation of disulfide scrambling during the enzymatic digestion of bevacizumab at various pH values using mass spectrometry. BBA - Proteins and Proteomics, 1864:9, 1188-94, 2016 陳頌方
期刊論文Yi-Fang Cheng, Guang-Huar Young, Tsu-Man Chiu, Jiun-Tsai Lin, Pei-Ru Huang, Cheng-Yi Kuo, Yao-Jen Liang, Po-Ku Chen, Sung-Fang Chen, Ching-Yi Cheng, Han-Min Chen*. Adenine supplement delays senescence in cultured human follicle dermal papilla cells. Experimental Dermatology, 25:2, 162-4, 2016 陳頌方
期刊論文Kung-Hao Liang, Chih-Lang Lin, Sung-Fang Chen, Chih-Wei Chiu, Pei-Ching Yang, Ming-Ling Chang, Chen-Chun Lin, Kai-Feng Sung, Cassandra Yeh, Chien-Fu Hung, Rong-Nan Chien, Chau-Ting Yeh*. GALNT14 genotype effectively predicts the therapeutic response in unresectable hepatocellular carcinoma treated with transcatheter arterial chemoembolization. Pharmacogenomics, 17:4, 353-66, 2016 陳頌方
期刊論文 Chih-Wei Chiu, Han-Min Chen, Tzong-Ta Wu, Ying-Chu Shih, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ling Hsu, Sung-Fang Chen*. Differential Proteomics of Monosodium Urate Crystals-Induced Inflammatory Response in Dissected Murine Air Pouch Membranes by iTRAQ Technology. Proteomics, 15:19, 3338-48, 2015 陳頌方
期刊論文Chih-Wei Chiu, Sung-Fang Chen*. Peptide Fractionation by Multidimensional Liquid-based Separation Techniques for Proteomic Analysis. CHEMISTRY (The Chinese Chemical Society, Taipei), 73:1, 57-66, 2015 陳頌方
期刊論文Huang-Joe Wang, Sung-Fang Chen*, Wan-Yu Lo*. iTRAQ quantitative proteomics-based identification of cell adhesion as a dominant phenotypic modulation in thrombin-stimulated human aortic endothelial cells. Thrombosis Research, 135:5, 944-50, 2015 陳頌方
期刊論文Yi-Ting Chen, Li-Ping Tuan, Hsiao-Wei Chen, I-An Wei, Min-Yuan Chou, Han-Min Chen, Yu-Chang Tyan, Sung-Fang Chen*. Quantitative Analysis of Prostate Specific Antigen Isoforms Using Immunoprecipitation and Stable Isotope Labeling Mass Spectrometry. Analytical Chemistry, 87:1, 545-553, 2015 陳頌方
期刊論文 Sheng-Yu Huang, Sung-Fang Chen, Chun-Hao Chen, Hsuan-Wei Huang, Wen-Guey Wu, Wang-Chou Sung*. Global Disulfide Bond Profiling for Crude Snake Venom Using Dimethyl Labeling Coupled with Mass Spectrometry and RADAR Algorithm. Analytical Chemistry, 86:17, 8742–8750, 2014 陳頌方
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