陳頌方
姓名 陳頌方
電子郵件
聯絡電話 (02)7749-6180
實驗室電話 (02)7749-6210
職稱 教授
研究領域 分析化學、生化質譜分析、層析分離
指導學生 廖琬柔、林姵岑、王瀞嬴、蘇怡瑄、黃婉慈、鄧介恩、江坤壕、吳冠履
實驗室 生化質譜研究室
年度 論文名稱
2023 A Review of Liquid Chromatography-Mass Spectrometry Strategies for the Analyses of Metabolomics Induced by Microplastics, Separations, vol. 10, Apr. 2023
2023 Characterizing different types of black fountain pen ink using the chemical approach, Journal of the Chinese Chemical Society, vol. 1, Mar. 2023
2022 Oncogenic Roles of Polycomb Repressive Complex 2 in Bladder Cancer and Upper Tract Urothelial Carcinoma, Biomedicines, vol. 10, Nov. 2022
2022 Quantification of anthocyanosides in grapes by QuEChERS and biphenyl-UHPLC tandem mass spectrometry, Journal of Food and Drug Analysis, vol. 30, Jul. 2022
2022 Quantification of anthocyanins in blueberries (Vaccinium spp.) by modified QuEChERS and liquid chromatography-mass spectrometry, Journal of the Chinese Chemical Society, vol. 69, Jul. 2022
2022 Analysis of highly polar pesticides in foods by Liquid Chromatography-Mass Spectrometry, Journal of Food and Drug Analysis, Jun. 2022
2022 Targeted Protein Quantitation in Human Body Fluids by Mass Spectrometry, Mass Spectrometry Reviews, Jun. 2022
2022 The Use of Atmospheric-Pressure Chemical Ionization for Pesticide Analysis Using Liquid Chromatography Mass Spectrometry, Journal of Food and Drug Analysis, vol. 30, Mar. 2022
2021 Analysis of Heterocyclic Aromatic Amines using Selective Extraction by Magnetic Molecularly Imprinted Polymers Coupled with Liquid Chromatography – Mass Spectrometry, Journal of Food and Drug Analysis, vol. 29, Dec. 2021
2021 Tenofovir Hampers the Efficacy of Sorafenib in Prolonging Overall Survival in Hepatocellular Carcinoma, Biomedicines, vol. 9, Oct. 2021
2021 Quick screening of true tyrosinase inhibitors from natural products using tyrosinase-immobilized magnetic nanoparticles and a magnetic microplate: Part II melanogenesis bioactivity, Journal of the Chinese Chemical Society, vol. 1, Sep. 2021
2020 Quantifification of Adenosine Mono-, Di- and Triphosphate from Royal Jelly using Liquid Chromatography - Tandem Mass Spectrometry, Journal of Food and Drug Analysis, vol. 28, Aug. 2020
2019 Comparison of different fractionation strategies for in-depth phosphoproteomics by liquid chromatography tandem mass spectrometry, Analytical and Bioanalytical Chemistry, vol. 411, Jun. 2019
2019 Analysis of heterocyclic amines in meat products by liquid chromatography - Tandem mass spectrometry, Journal of Food and Drug Analysis, vol. 27, Apr. 2019
2019 Monitoring the Disulfide Bonds of Folding Isomers of Synthetic CTX A3 Polypeptide Using MS-Based Technology, Toxins, vol. 11, Jan. 2019
2018 Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein, FIP-fve, extract from Flammulina velutipes, Journal of Food and Drug Analysis, vol. 26, Jul. 2018
2018 Combination of on-line desalting and HPLC-UVESI-MS for simultaneous detection and identification of FIP-fve and flammutoxin in Flammulina velutipes, Journal of Food and Drug Analysis, vol. 26, Jul. 2018
2018 Quantification of trans-resveratrol in red wines using QuEChERS extraction combined with liquid chromatography - tandem mass spectrometry, Analytical Sciences, vol. 34, Apr. 2018
2018 Comparison of Poly(Styrene-Divinylbenzene)-based Monolithic and Bead-based Methodologies Used in NANOFLOW LCMS for Proteomic Studies, Analytical Methods, vol. 10, Jan. 2018
2018 Identifying Specific and Differentially Linked Glycosyl Residues in Mammalian Glycans by Targeted LC-MS, Analytical Sciences, vol. 34, Jan. 2018
2017 A Brief Review of Bioinformatics Tools for Glycosylation Analysis by Mass Spectrometry, Mass Spectrometry (Tokyo), vol. 6, Feb. 2017
2016 Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics, Scientific Reports, vol. 6, Oct. 2016
2016 Evaluation of disulfide scrambling during the enzymatic digestion of bevacizumab at various pH values using mass spectrometry, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol. 1864, Sep. 2016
2016 GALNT14 genotype as a therapeutic response predictor for unresectable hepatocellular carcinoma treated by transcatheter arterial chemoembolization, Pharmacogenomics, vol. 17, Mar. 2016
2016 Adenine supplement delays senescence in cultured human follicle dermal papilla cells, Experimental Dermatology, vol. 162, Feb. 2016
2015 Differential Proteomics of Monosodium Urate Crystals-Induced Inflammatory Response in Dissected Murine Air Pouch Membranes by iTRAQ Technology, Proteomics, vol. 15, Oct. 2015
2015 iTRAQ quantitative proteomics-based identification of cell adhesion as a dominant phenotypic modulation in thrombin-stimulated human aortic endothelial cells, Thrombosis Research, vol. 135, May. 2015
2015 Peptide Fractionation by Multidimensional Liquid-based Separation Techniques for Proteomic Analysis, Chemistry (The Chinese Chemical Society, Taipei), vol. 73, Mar. 2015
2015 Quantitative Analysis of Prostate Specific Antigen Isoforms Using Immunoprecipitation and Stable Isotope Labeling Mass Spectrometry, Analytical Chemistry, vol. 87, Jan. 2015
2014 Global Disulfide Bond Profiling for Crude Snake Venom Using Dimethyl Labeling Coupled with Mass Spectrometry and RADAR Algorithm, Analytical Chemistry, vol. 86, Aug. 2014
2013 Mass spectrometry-based strategies for protein disulfide bond identification, Reviews in Analytical Chemistry, vol. na, Aug. 2013
2013 Differential Proteomic Analysis of Cancer Stem Cell Properties in Hepatocellular Carcinomas by Isobaric Tag Labeling and Mass Spectrometry, Journal of Proteome Research, vol. 12, Jun. 2013
2013 Essential role of β-human 8-oxoguanine DNA glycosylase 1 in mitochondrial oxidative DNA repair, Environmental and Molecular Mutagenesis, vol. 54, Jan. 2013
2012 Evaluation of peptide fractionation strategies used in proteome analysis, Journal of Separation Science, vol. 35, Dec. 2012
2012 miR-27b-Regulated TCTP as a Novel Plasma Biomarker for Oral Cancer: From Quantitative Proteomics to Post-Transcriptional Study, Journal of Proteomics, vol. 77, Dec. 2012
2012 Automatic Disulfide Bond Assignment Using a1 Ion Screening by Mass Spectrometry for Structural Characterization of Protein Pharmaceuticals, Analytical Chemistry, vol. 84, Jun. 2012
2010 Comparative proteomic profiling of plasma very-low-density and low-Density lipoproteins, Clinica Chimica Acta, vol. 411, Mar. 2010
2010 Nonmuscle myosin IIA (myosin heavy polypeptide 9): a novel class of transducer mediating the activation of G alpha h/phospholipase C- delta 1 pathway, Endocrinology, vol. 151, Mar. 2010
2009 Protein Profilings in Mouse Liver Regeneration after Partial Hepatectomy using iTRAQ Technology, Journal of Proteome Research, vol. 8, Feb. 2009
2008 The possible interaction of CDA14 and protein elongation factor 1α, Biochimica et Biophysica Acta, vol. 1784, Feb. 2008
2008 Screening, purification, and identification of a copper-dependent FITC-binding protein in human plasma: Albumin, Journal of Chromatography B, vol. 863, Feb. 2008
2007 Powerful tools for biomarker discovery: An overview of differential proteomics, Chemistry (The Chinese Chemical Society, Taipei), vol. 65, Jun. 2007
2006 Subcellular and Functional Proteomic Analysis of the Cellular Responses Induced by Helicobacter pylori, Molecular & Cellular Proteomics, vol. 5, Apr. 2006
2005 Assembly of homotrimeric type XXI minicollagen by coexpression of prolyl 4-hydroxylase in stably transfected Drosophila melanogaster S2 cells, Biochemical and Biophysical Research Communications, vol. 336, Oct. 2005
2002 Structural Characterization of Escherichia coli Sialic Acid Synthase, Biochemical and Biophysical Research Communications, vol. 295, Jul. 2002
1997 Electrochemical enzyme immunoassay for serum prostate-specific antigen at low concentrations, Clinical Chemistry, vol. 43, Aug. 1997
年度 論文名稱
2017 Analysis of Heterocyclic Aromatic Amines in Meat Products by Liquid Chromatography - Tandem Mass Spectrometry, 2017 中國化學會年會, Dec. 01-02, 2017, 嘉義
2017 Monitoring protein refolding process by analyzing the disulfide bonds of intermediates using mass spectrometry, HUPO 2017, Sep. 17-21, 2017, Dublin, Ireland
2017 Glycoproteome-wide identifications of novel GALNT14 substrates using tandem mass spectrometry, Shimadzu Global Innovation Summit 2017, Jul. 04-05, 2017, Kyoto, Japan
2017 Comparison among Different Fractionation Approaches in Human Serum Proteome and the Effects on Protein Profile with the Depletion Kit Treatment, TSMS 2017, Jun. 28-30, 2017, 台中
2016 Evaluation of Disulfide Scrambling at Various pH on Avastin Digestion by Mass Spectrometry, 2016 中國化學會年會, Dec. 03-04, 2016, 台中
2016 Quantitative analysis of prostate specific antigen isoforms using immunoprecipitation and stable isotope labeling mass spectrometry, APFCB 2016, Nov. 26-29, 2016, 台北
2016 Comparison of SDVB-Monolithic & Bead-based Methodologies Used in NANOFLOW LCMS for Proteomic Study, Proteomics Congress 2016, Oct. 24-26, 2016, Rome, Italy
2016 Comparison of Different Fractionation Approaches for the Human Serum Proteome and their Effects on Protein Profiles by Treatment with a Depletion Kit, HUPO 2016, Sep. 18-21, 2016, 台北
2016 Quantitative analysis of prostate specific antigen isoforms using immunoprecipitation and stable isotope labeling mass spectrometry, The 3rd Joint Symposium of NTUT, NTNU and OPU on Chemistry, Sep. 05-07, 2016, Osaka, Japan
2016 質譜技術在食品蛋白質體學之應用, TSMS 2016, Jun. 27-29, 2016, 高雄
2016 Quantification of Trans-Resveratrol in Red Wines using QuEChERS Extraction and Liquid Chromatography – Tandem Mass Spectrometry, 第23屆分析技術交流研討會, May. 21, 2016, 高雄
2015 Quantitative analysis of prostate specific antigen isoforms using immunoprecipitation and isotope dilution mass spectrometry, 2015 MSCD (Mass Spectrometry for Clinical Diagnosis), Nov. 06-07, 2015, 中山大學
2015 Comparison of SDVB-Monolithic & Bead-based Columns Used in Nanoflow LC/MS for Proteomic Study, TSMS 2015, Jul. 13-15, 2015, 新竹
2015 Differential Proteomics of Monosodium Urate Crystals-Induced Responses in Dissected Murine Air Pouch Membranes by iTRAQ Technology, 第22屆分析技術交流研討會, May. 21, 2015, 高雄
2015 Comparison of SDVB-Monolithic & Bead-based Columns Used in Nanoflow LC/MS for Proteomic Study, MSACL 2015, Mar. 28-Apr. 01, 2015, San Diego, USA
2014 Quantitative analysis of prostate specific antigen isoforms using immunoprecipitation and isotope dilution mass spectrometry, 2014 MSCD (Mass Spectrometry for Clinical Diagnosis), Nov. 07-08, 2014, 中山大學
2014 Quantitative analysis of prostate specific antigen isoforms using immunoprecipitation and isotope dilution mass spectrometry, IMSC 2014, 20th International Mass Spectrometry Conference, Aug. 24-29, 2014, Geneva, Switzerland
2014 Quantitative Analysis of Prostate Specific Antigen Isoforms using Immunoprecipitation and Isotope Dilution Mass Spectrometry, TSMS 2014, Jun. 29-Jul. 01, 2014, 台中
2014 Comparative Proteomic Profiling by Isobaric Tag Labeling and Mass Spectrometry, 第十一屆台灣質譜學會學術研討會暨2014年質譜年會, Jun. 29-Jul. 01, 2014, 中興大學
2014 Differential Proteomic Analysis of Acute and Chronic Hepatitis C Virus Infection using iTRAQ-based Technology, 2014台灣蛋白體學會夏季研習會, May. 30-31, 2014, 成功大學
2013 Differential Proteomic Analysis of Cancer Stem Cell Properties in Hepatocellular Carcinomas by Isobaric Tag Labeling and Mass Spectrometry, 4th AOMSC & 10th TSMS Annual Conference, Jul. 10-12, 2013, Taipei, Taiwan
2013 miR-27b-Regulated TCTP as a Novel Plasma Biomarker for Oral Cancer: From Quantitative Proteomics to Post-Transcriptional Study, 61st ASMS Conference on Mass Spectrometry and Allied Topics, Jun. 09-13, 2013, Minneapolis
2013 質譜技術在食品成分分析之應用, 2013農產品成份與功能分析研討會, Jun. 03, 2013, 台北市
2012 Evaluation of peptide fractionation strategies used in proteome analysis, IMSC 2012, Sep. 15-Oct. 21, 2012, kyoto, Japan
2012 Automatic Disulfide Bond Assignment Using a1 Ion Screening by Mass Spectrometry for Structural Characterization of Protein Pharmaceuticals, IMSC 2012 - 19th International Mass Spectrometry Conference, Sep. 15-21, 2012, Kyoto, Japan
2012 Phosphoproteomic Analysis of LPS-treated RAW264.7 by IMAC/TiO2-MOAC Enrichment and Mass Spectrometry, 第四屆世界華人質譜研討會暨2012年台灣質譜年會, Jun. 28-Jul. 01, 2012, 成功大學
2012 Evaluation of Peptide Fractionation Strategies Used in Proteomic Analysis Of PLC/PRE/5 cell line, 第四屆世界華人質譜研討會暨2012年台灣質譜年會, Jun. 28-Jul. 01, 2012, 成功大學
2012 Comparison of fused-core with conventional 3 μm porous silica particles used in capillary columns of LC-MS/MS for proteomic study, 第四屆世界華人質譜研討會暨2012年台灣質譜年會, Jun. 28-Jul. 01, 2012, 成功大學
2011 BEL-K Target Candidate Identification by Affinity Chromatography and Mass Spectrometry, 第八屆台灣質譜學會學術研討會暨2011年質譜年會, Jul. 10-12, 2011, 中央研究院
2011 Disulfide linkage analysis of Herceptin using automatic a1 ion screening and custom-made software RADAR, 第八屆台灣質譜學會學術研討會暨2011年質譜年會, Jul. 10-12, 2011, 中央研究院
2011 Differential proteomic analysis of cancer stem cell properties in HCC by isobaric tags labeling approach, 第十七屆分析化學技術交流研討會, May. 14-15, 2011, 國立中興大學蕙蓀林場
2010 Disulfide bond analysis using automatic a1 ion screening and its application to structural characterization of protein pharmaceuticals, The 1st Asian and Oceanic Mass Spectrometry Conference, Jun. 16-18, 2010, Tsukuba, Japan
2007 Protein Profilings in Mouse Liver Regeneration after Partial Hepatectomy using iTRAQ Technology, ASMS Conference 2007, Jun. 03-07, 2007, Indianapolis, USA
2004 Mass Spectrometric Characterization of Monascus sp. Proteins Utilizing an Integrated Platform, ASMS Conference 2004, May. 28-Jun. 01, 2004, Nashville, USA
2003 Improved peptide mapping of proteins with multiple enzymatic digestions and mass spectrometry, ASMS Conference 2003, Jun. 08-12, 2003, Montreal, Canada
2001 Specific Binding of Ru complexes with Oligonucleotides Studied by Electrospray Ionization Tandem Mass Spectrometry, Denmark-Taiwan Biological Inorganic Chemistry Symposium, May. 21, 2001, Taipei, Taiwan
年度 書名
2015 質譜數據解析, 質譜分析技術原理與應用, 全華圖書股份有限公司, 978-957-21-9992-3, Oct. 2015
年度 計畫名稱 職稱/擔任之工作 計畫期間 補助/委託或合作機構
2023 多體學技術開發並應用於塑膠微粒對小鼠之毒性研究(1/3) 主持人 2022.08 ~ 2023.07 科技部(原國科會)
2022 利用分子印跡技術與液相層析質譜技術分析複雜基質中之蛋白質分子 主持人 2019.08 ~ 2022.07 科技部(原國科會)
2019 雜環胺類化合物之分析方法開發與其生化作用機制之探討(3/3) 主持人 2018.08 ~ 2019.07 科技部(原國科會)
2018 雜環胺類化合物之分析方法開發與其生化作用機制之探討(2/3) 主持人 2017.08 ~ 2018.07 科技部(原國科會)
2017 雜環胺類化合物之分析方法開發與其生化作用機制之探討(1/3) 主持人 2016.08 ~ 2017.07 科技部(原國科會)
2016 同位素化學標記法搭配質譜技術進行發炎反應動物模式之差異蛋白質體學研究 主持人 2015.08 ~ 2016.07 國科會
2015 同位素化學標記法搭配質譜技術進行發炎反應動物模式之差異蛋白質體學研究 主持人 2014.08 ~ 2015.07 國科會
2014 同位素化學標記法搭配質譜技術進行發炎反應動物模式之差異蛋白質體學研究 主持人 2013.08 ~ 2014.07 國科會
2014 同位素化學標記法搭配質譜技術進行發炎反應動物模式之差異蛋白質體學研究 主持人 2013.08 ~ 2014.07 國科會
2013 化學藥物蛋白質體技術研究 主持人 2012.08 ~ 2013.07 國科會
2012 化學藥物蛋白質體技術研究 主持人 2011.08 ~ 2012.07 國科會
2011 定量蛋白質體技術之開發與應用研究 主持人 2010.08 ~ 2011.07 國科會
2010 定量蛋白質體技術之開發與應用研究 主持人 2009.11 ~ 2010.07 國科會
國家 學校名稱 系所 學位 期間
美國 克里夫蘭州立大學 化學所 博士 1994.09 ~ 2000.06
台灣 國立中山大學 化學系 學士 1988.09 ~ 1992.06
服務機關名稱 單位 職務 期間
國立臺灣師範大學 化學系 教授 2019.02 ~ 迄今
國立臺灣師範大學 化學系 副教授 2013.02 ~ 2019.01
國立臺灣師範大學 化學系 助理教授 2009.08 ~ 2013.01
工業技術研究院 生醫所 研究員、經理 2002.06 ~ 2009.08
中央研究院 化學所 博士後研究 2000.08 ~ 2002.06
Cleveland Clinic Foundation Allogen Labs Research Assistant 1996.06 ~ 2000.07